Size associated markers

Breed-Defining Chondrodysplasia

Breed-defining chondrodysplasia, also called short-leggedness, is a favorable phenotype found in some breeds. The well-known features of this breed-defining trait are caused by the FGF4 retrogene insertion. Short-leggedness caused by the FGF4 insertion is a desirable trait, and it is caused by different mutation than the undesired dwarfism causing genetic disorder found in some breeds, such as the Norwegian Elkhound.

The Dog’s Genetic Size – The Strong and Weak Size Markers

Understanding canine genetic size may be an important tool in the future, for instance, in planning of individual care, such as weight control. Previously we introduced the new size markers added to the MyDogDNA test panel. In this blog article, we will give a deeper insight into the effects of these markers.

Understanding the Dog's Genetic Size Facilitates Planning Individual Care and Weight Control

MyDogDNA has now added four new size associated genetic markers called GHR1, GHR2, HMGA2, STC2and a test for breed-defining chondrodysplasia to the test panel. These markers, together with the previously reported size associated markers in IGF1 and IGF1R give more information on the dog size, supporting finer prediction of the genetic size of a dog.