MyDogDNA News

Clinical perspective: Bleeding disorders

Many different types of hereditary bleeding disorders have been encountered in dogs, some of which are quite common in certain breeds (Table 1). Most of these cause spontaneously only mild bleeding, such as nosebleeds or bleeding of the gums. However, many bleeding disorders can cause excessive, even life-threatening, bleeding after surgery or trauma.

Table 1. The occurrence of certain common bleeding disorders in certain breeds

New test content for Labrador Retrievers and Jack Russell Terriers

Genetic tests for mutations causing Congenital Myasthenic Syndrome in Labrador Retrievers and Jack Russell Terriers are now available in the MyDogDNA 2016 test panel. The disorder is considered severe, typically with an early onset of symptoms. See a more detailed description below.

New study on the canine breed disease heritage gives a comprehensive insight into the breed distribution of disease related genetic risk variants

The MyDogDNA research team of Genoscoper Laboratories Oy, Finland, has in collaboration with scientists from the University of Helsinki, Finland, and University of Pennsylvania, Philadelphia, USA, published the results from the most comprehensive investigation into the canine breed disease heritage to date.

Soon in the MyDogDNA test panel: Developmental Syndrome in Wire Fox Terriers

The genetic cause for a previously undescribed skeletal syndrome in Wire Fox Terriers was recently revealed in a publication by the canine genetics research group at the University of Helsinki. Genoscoper will soon be the first laboratory in the world to offer the genetic test for this condition in the MyDogDNA test panel.

Test soon available for Dental hypomineralization in Border Collies

The canine genetics research group at the University of Helsinki published a study in May revealing the genetic causes for three hereditary disorders. With the novel gene discoveries the research group was able to identify the genetic causes for hyperostosis in Terrier breeds, dental hypomineralization in Border Collie, and previously undescribed skeletal syndrome in Wire Fox Terriers.

Clinical perspective: the MDR1 mutation

I work as an on-duty veterinarian providing emergency care for pets. My patients are often seriously ill and require intensive medical care; decisions have to be made rapidly. For many of my patients, adverse reactions in response to drugs could potentially be severe. As a veterinarian, I would prefer that at least each of my Collie, Australian Shepherd and Shetland Sheepdog patients would be tested for MDR1 mutation before starting treatment. In this article I will tell you why.

Color Pattern (RALY gene): Saddle Tan

In addition to other new test results for coat colors, one more test result is now available for all MyDogDNA 2015 tested dogs:

Color Pattern (RALY gene): Saddle Tan

To learn more about what this result means, read the test description below:

"RALY gene defines whether tan points or saddle tan is expressed in the dog's phenotype in breeds that express both colors. 

New Improved User Experience in the Database

To make your user experience more comfortable we have published the following features:

  • You can edit the editable fields in the dog profile by clicking the field itself. To edit other fields, please contact our customer service for assistance.

  • The dog's tags and Breeder Tool description can now also be edited easily in their own fields.

Test for dilution (D locus) as a marker gene test for certain breeds now in the MyDogDNA panel

We are introducing one more genetic test for coat colors in the MyDogDNA test panel. As a result of research and development work, we have now included a beta phase marker test for dilution for the following breeds:

Heads, tails and all that jazz…

As soon as a baby is born, families usually start arguing about whom the baby looks like. The same with puppies: head from mom, tail from dad and so on... And then begins the big debate on how to name the babies.

Recessive Black (allele a) - Latest Addition to MyDogDNA Color Tests

The MyDogDNA test panel includes now a new genetic test for coat colors: The a allele in the color locus A. The result is available to all MyDogDNA 2015 tested dogs on the "Traits" tab.

The A-locus, also known as the ASIP gene, affects the production of the pigment molecule responsible for black color. Four different alleles are known at the A locus: ay, aw, at and a allele.

MyDogDNA as breeding tool for Cirneco dell’Etnas

Although considered as one of the oldest breeds in Europe, according to present knowledge, the global population of our breed, Cirneco dell’Etna, is relatively small. Cirneco-like dogs have appeared on the Italian island of Sicily for about three thousand years. During the last centuries the Cirnecos have been used in hunting wild rabbits on the challenging slopes of the volcano Etna.

Dog’s Genotype and Colors

The color of a dog’s coat depends on the combined effect of many different genetic variants. Although all genes and alleles have not yet been identified, many factors and combinations are known to have effect on the final appearance of the dog. Due to the complexity of the possible combinations, as well as the hierarchy of the factors, reading the results of genetic tests for colors is not all straightforward. In order to facilitate the interpretation of the MyDogDNA test results, we have drawn the descriptive chart presented below.

Puppies, puppies, puppies!

Rita’s puppies were born on exactly 62 days after the mating. As I am writing this they are 3.5 weeks old, cute beyond any verbal description and getting more active every day.​

New Test: Color Locus S (Piebald or Extreme White Spotting)

Domestic dogs have great diversity in white spotting patterns ranging from extreme white to minimal white or completely solid color. The amount of white color is determined by genetic factors as well as by stochastic events in pigment cell development. It is important to understand that white color in domestic dogs is controlled by many variants as well as random events in the maturation of the cells.

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