Cystinuria Research – Recruitment of Dogs!

Cystinuria is a hereditary condition that causes the formation of cystine stones in the urinary tract. Urinary tract stones cause pain when urinating, bloody urine, and blockage of the urinary tract. Blockage of the urinary tract is a life-threatening condition that requires immediate veterinary care. Cystine stones occur predominantly in male dogs (98 %). 

There are different forms of urinary tract stones with different compositions. The composition of the stone can be studied after it is removed from the urinary tract. Cystine stones are a rare urinary tract stone type that has a genetic predisposition. Cystine stones have higher occurrence rates in some breeds.

Do you have an English Bulldog or French Bulldog diagnosed with cystinuria? – Participate!

There is some scientific evidence of certain genetic variants increasing risk for cystinuria in English Bulldogs and French Bulldogs. However, more scientific evidence would still be beneficial before a predictive genetic test can responsibly be provided to the breed communities. We are studying cystinuria further, and exploring the opportunity for a genetic test for the condition. Please feel free to contact if your English Bulldog of French Bulldog has been diagnosed with cystinuria, and hear what we have to offer to you in return.

Other molossoid-type breeds also needed

We are also studying predisposition to cystinuria in several other molossoid breeds. Please feel free to contact if your dog has been diagnosed with cystinuria, to hear if your dog is eligible for inclusion in our study.