OptiGen Collie Eye Anomaly and prcd-PRA tests available as MyDogDNA add-ons for 20 Euros each!

We have exciting news to share! You may have heard that Wisdom Health™, the world leader in canine genetic testing, acquired OptiGen Laboratories® in April 2018. By joining forces, we are able to leverage our combined expertise, commitment to quality, and research efforts to bring you an even more complete and comprehensive panel for use in your breeding program.

As part of this merger, Genoscoper Laboratories and Wisdom Health™ are now able to offer the patented OptiGen® Collie Eye Anomaly and OptiGen® prcd-PRA mutation tests. These mutation tests will be offered as add-on tests to the MyDogDNA® and Optimal Selection™ Canine Genetic Breeding Analysis for only 20 Euros each!

The results of the Collie Eye Anomaly and prcd-PRA add-on tests will be reported in the MyDogDNA®/Optimal Selection™ report; you can submit the results to the Orthopedic Foundation for Animals and national kennel clubs as an officially recognized OptiGen® test result.

Taking advantage of this new test feature is simple! Existing customers with recent results may purchase the OptiGen® tests directly from their disease report by clicking “Buy Test” next to the mutation test desired. Results will be updated within 24 hours of purchase.

To order the add-on test(s), please follow these steps:

1.    Log into your account
2.    Click on dog’s name to access their report
3.    Click on the DISORDERS tab
4.    From the DISORDERS section, click on ‘Buy Test’ next to the mutation you wish to purchase as an add-on
5.    You will be redirected to the MyDogDNA.com webshop
6.    Follow on screen instructions to purchase the add-on(s)
7.    Once the order is received, the results will be updated with the additional information within 24 hours.

Customers who tested on prior versions of the test may have to upgrade to the latest version of the Optimal Selection™ or MyDogDNA® panel test in order to gain access to the Optigen® tests as well as the latest additions to the panel. This will require a retest. You can upgrade for only 40 Euros plus the add-on test fees. A new kit will be shipped to you.

 

Descriptions of the tests:

Collie Eye Anomaly, (CEA)

Collie Eye Anomaly (CEA) is a congenital hereditary ocular disease found in multiple breeds of herding descent. The severity of the disease varies greatly between dogs: mildly affected dogs can have puppies that are severely affected and vice versa. The disorder is inherited in an autosomal recessive manner.

The mildest form of the disease is choroidal hypoplasia (CH). Choroidal hypoplasia is non-progressive and usually does not cause visual deficits on its own. Mild changes associated with this disease are typically best visualized with ophthalmoscopy in puppies before 10 weeks of age. Colobomas occur in a more severe form of the disease. Colobomas of the optic disc are excavations of the optic disc surface. Large colobomas may lead to reduced vision while smaller ones have little effect on vision. Retinal detachment or bleeding inside the eye can develop in severely affected dogs as a secondary complication of coloboma. This can cause loss of vision. Sometimes the eyeballs of affected dogs can be distinctly smaller in size than normal.

To date, the mutation has been encountered in the following breeds: Australian Shepherd, Bearded Collie, Berger d'Auvergne, Border Collie, Boykin Spaniel, Collie, Collie Rough, Collie Smooth, English Shepherd, Hokkaido, Lancashire Heeler, Miniature American Shepherd, Mixed breed, Nova Scotia Duck Tolling Retriever, Shetland Sheepdog, Silken Windhound, Whippet

prcd-PRA

Progressive retinal atrophy is the common name for a family of hereditary retinal dystrophies commonly leading to blindness. PRA is found in more than 100 dog breeds but the genetic background varies among breeds and populations. prcd-PRA is a very common form of PRA. This disease is caused by the degeneration of photoreceptor cells of the retina. The disorder is inherited in an autosomal recessive manner.

prcd-PRA is a progressive, hereditary ocular disorder causing retinal degeneration. The rod-photoreceptors that are needed for vision in low light levels are the first to degenerate. The first sign of the disorder is thus often night-blindness. Cone-photoreceptors that work in full light degenerate later resulting in full blindness. The age of onset in prcd-PRA varies greatly between breeds but is typically present in early adulthood.

To date, the mutation has been encountered in the following breeds: American Cocker Spaniel, American Eskimo Dog, American Hairless Terrier, Australian Cattle Dog, Australian Shepherd, Australian Silky Terrier, Australian Stumpy Tail Cattle Dog, Barbet, Black Russian Terrier, Bolognese, Bolonka, Chesapeake Bay Retriever, Chihuahua, Chihuahua – Longhaired, Chihuahua - Smooth-haired, Chinese Crested Dog, Coton de Tulear, English Cocker Spaniel, Entlebucher Mountain Dog, Field Spaniel, Finnish Lapphund, Giant Schnauzer, Giant Schnauzer – Black, Giant Schnauzer - Pepper and salt, Golden Labrador Retriever, Golden Retriever, Goldendoodle, Karelian Bear Dog, Kuvasz, Labrador Retriever, Lagotto Romagnolo - Romagna Water Dog, Lancashire Heeler, Lapponian Herder, Manchester Terrier – Toy, Miniature American Shepherd, Mixed breed, Norrbottenspitz, Norwegian Elkhound, Black,  Norwegian Elkhound, Grey, Nova Scotia Duck Tolling Retriever, Plott, Poodle (AKC), Poodle - Medium size (FCI size standard) - Black, brown and white, Poodle - Medium size (FCI size standard) - Grey, apricot and red, Poodle - Miniature (AKC size standard), Poodle - Miniature (FCI size standard) - Black, brown and white, Poodle - Miniature (FCI size standard) - Grey, apricot and red, Poodle - Standard (AKC size standard), Poodle - Standard (FCI size standard} - Black, brown and white, Poodle - Standard (FCI size standard) - Grey, apricot and red, Poodle - Toy (AKC size standard), Poodle - Toy (FCI size standard), Portuguese Podengo, Portuguese Podengo – Miniature, Portuguese Podengo - Smooth­haired Miniature, Portuguese Podengo - Wirehaired Miniature, Portuguese Water Dog, Rat Terrier, Schipperke, Spanish Water Dog, Swedish Elkhound, Swedish Lapphund, Xoloitzcuintle, Yorkshire Terrier