Ivermectin

Clinical perspective: the MDR1 mutation

I work as an on-duty veterinarian providing emergency care for pets. My patients are often seriously ill and require intensive medical care; decisions have to be made rapidly. For many of my patients, adverse reactions in response to drugs could potentially be severe. As a veterinarian, I would prefer that at least each of my Collie, Australian Shepherd and Shetland Sheepdog patients would be tested for MDR1 mutation before starting treatment. In this article I will tell you why.